Functional Assays
& Assay Development

• Tumors are generated by injection of appropriate tumor cells into C57BL mice (mouse tumors) or into immune-compromised SCID or nude mice (human tumors)
• 10 mice for each: compound (1 dose) and vehicle control
• Treatments are given daily (s.c. or i.p.) or as instructed by the client
• Typical treatments continue for 2-4 weeks
• Data collected includes: tumor volume (mm3), tumor weight at the end of study, and histology sections (if requested by the client)
• Several tumor lines (mouse and human) are already available at Paragon (no extra cost) - clients would have to provide unique lines
• Client receives a detailed report summarizing original data in graphs and including basic statistics

Contact Paragon Bioservices to discuss your specific needs