Electron Microscopy

			Electron Microscopy Services
			Electron Microscopy Services

Electron Microscopy Services have been designed at Paragon Bioservices to support research protocols performed at Pharmaceutical and Biotechnology companies as well as Academic Laboratories spanning the fields of Virology, Cell Biology and Gene Therapy.

All contracted services are performed by experienced scientists (Ph.D., MD-Ph.D.) and technicians qualified to review pertinent literature and to make recommendations to the contracting laboratory.


	Catalog No. Complete TEM Service Complete SEM Service	70001-11 70020-00
	A complete TEM or SEM service includes all processing, embedding, thick and thin sectioning, as well as microscopic analysis. Following the transmission and/or scanning EM, photographic documentation (10-12 8x10 photographs) of important morphologies will be provided to the contraction laboratory.

Superior technical expertise and familiarity with the scientific objectives of our clients are the cornerstone of Paragon's success in Electron Microscopy Services.	Processing, Embedding, Thick and Thin Sectioning Processing and Embedding Thin Sectioning from an existing block Thick Sectioning from an existing block Duplicate Micrographs (8x10),each Negative Staining - Routine Negative Staining - Quantitative	70014-02 70016-02 70014-01 70016-01 70019-00 70040-00 70041-00

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Stains and Images

Electron Microscopy

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Mouse Embryos

	Routine negative staining for either TEM or SEM includes processing of the samples, application on to grids, microscopic analysis of surface morphology, and photographic documentation. Quantitative negative staining also involves the counting of particles, including viruses. Statistical analysis is also performed.
	Immunogold Labeling	70030-00
Immunogold labeling is a method used for the localization of specific antigens at the EM level. Samples are fixed (using lower concentrations of glutaraldehyde), processed, and sectioned. The grids are immunostained using an antigen-specific primary antibody followed by a gold-labeled secondary antibody. Electron-dense gold particles localize to the desired antigens within ultastructural components and organelles of cells.

Cell Culture & Fermentation Services
Recombinant Protein Expression | Protein Purification
Proteomics Services - Protein Characterization
Virus Production & Purification | Process Development
Functional Assays & Assay Development | Histology & Immunohistochemistry
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