Process development bridges the distance between the research bench and GMP manufacturing. It defines a set of specific objectives to ensure the production of a protein will be scalable, reproducible and cost-effective.
Collectively, Paragon's upstream and downstream scientists and engineers currently produce and purify 75 to 150 individual proteins per year.
Specific process development services include:
- Gene and vector optimization
- Best expressor analysis
- Cell line development
- Cell banking - Working cell banks (WCBs)
- Expression optimization
- Homogenization - extraction
- Protein purification
- Functional assays