Angiogenesis assays are a specialization at Paragon - niche functional assays performed by experienced scientists.
In Vivo Assays
In vivo assays to demonstrate efficacy beyond the individual cell level.
- Matrigel / bFGF mouse angiogenesis assay – testing putative angiogenesis inhibitors and or activators
In Vitro Assays
Cell-based assays to demonstrate efficacy for specific targets in angiogenesis.
- Endothelial Cell (EC) Proliferation
- Smooth Muscle Cell Proliferation
- Endothelial Cell Migration
- Smooth Muscle Cell Migration
- Endothelial Cell Differentiation – Tube Formation
Ex Vivo Assays
- Ex Vivo vascular sprouting – robustly encompasses all three EC functions