Your
Outsourcing Partner
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| Paragon Bioservices is a cell
culture-based contract production and research services company
specializing in recombinant protein expression, protein
purification, adenovirus production and purification, recombinant
vaccines, process development, histology and
immunohistochemistry. Additional areas of expertise include neuroscience services, angiogenesis assays, and cell-based functional assays. |
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| Cell Banking | |||||||
| Recombinant Protein Expression |
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| Protein Purification |
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| Proteomics Services - Protein Characterization |
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| Virus Production & Purification |
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| Process Development |
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| Functional Assays & Assay Development Histology & Immunohistochemistry
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Cell Culture & Fermentation Services Paragon maintains a cell bank of mammalian and insect cells as well as bacterial strains which are utilized in research projects, for functional assays and assay development, for recombinant protein expression, for production of monoclonal antibodies, or as a source for sub-cellular fractions - purification of organelles, Hela nuclear extracts, and membrane preps. |
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| Recombinant Protein Expression Using multiple expression systems, Paragon has the capacity to produce up to gram quantities of recombinant proteins, including bacteria/yeast, baculovirus, and mammalian expression systems. Whether you're focused on lead discovery, production of identified targets for high throughput screening, or characterization of interesting gene products, we can help. |
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| Protein Purification A critical aspect in biopharmaceutical development is that expected functional activity must be associated with a single protein and that a formulation must be devoid of any contaminants including LPS, host cell DNA, viruses, etc. It is imperative, therefore, that therapeutic proteins, recombinant vaccines and diagnostic protein reagents be produced while achieving the highest level of purity possible. Combining its skills developed over the last 12 years in protein biochemistry, analytical chemistry, and funct?onal assays, Paragon delivers efficient and cost effective solutions in protein purification and process development under Good Laboratory Practices in anticipation of future GMP manufacturing needs. |
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| Proteomics Services - Protein Characterization Paragon is meeting the "proteomics" challenge - a new paradigm in pharmaceutical development involving the systematic study of the protein complement - the proteome, by providing our clients with such research services as purification of organelles and 2-D gel electrophoresis. |
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| Virus Production & Purification Paragon's capabilities in virus production and purification attempts to address critical national public health needs, including gene therapy (adenovirus and adeno-associated viruses - AAV's), recombinant vaccines (virus-like particles - VLP's), infectious diseases (bacteriophages). We further seek to serve our national security imperative of bioterrorism control via the production of simulant organisms. |
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| Process Development Technological advances in genomics, proteomics, target validation, and lead compound identification have created a substantial need for contract services along the entire length of the development pipeline. Paragon is a GLP-compliant, cost-effective, and expedient outsourcing partner to assist you through drug discovery and preclinical development. |
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| Functional Assays & Assay Development Outsourcing your in vitro, ex vivo, and in vivo biological assay needs to Paragon Bioservices frees up your capacity to allow you to pursue additional leads for drug development. |
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| Histology & Immunohistochemistry With average turnaround of five to seven days, Paragon offers histology services and a variety of special stains - plus on-site electron microscopy services. |
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Paragon Bioservices, Inc -
Johns Hopkins Bayview Research Campus Alpha Center - 5210 Eastern Avenue - Baltimore, Maryland 21224 800.545.6569 - 410.550.2919 - 410.550.2924 (fax) NIH BPA#: 263-00054123 - www.paragonbioservices.com - pbi@paragonbioservices.com |
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© 2003 Paragon Bioservices, Inc. |
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