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Paragon Bioservices is a cell culture-based contract production and research services company specializing in recombinant protein expression, protein purification, adenovirus production and purification, recombinant vaccines, process development, histology and immunohistochemistry.

     Additional areas of expertise include neuroscience services, angiogenesis assays, and cell-based functional assays.
Accelerate your drug discovery effortsRapid advances in genomics, proteomics, target validation, and lead compound identification demands cell culture production and research services to accelerate the discovery and preclinical development of biopharmaceuticals.

The development race is on...


Hand-off your cell-culture, protein expression, purification, and proteomics projects to Paragon Bioservicesfor additional capacity
or renewed energy...

pass your projects to
Paragon Bioservices

Cell Banking

Cell Culture &
Fermentation Services


Recombinant
Protein Expression

Protein Purification

Proteomics Services -
Protein
Characterization

Virus Production &
Purification

Process Development
 
Functional Assays &
Assay Development


Histology &
Immunohistochemistry


Paragon Bioservices, Inc., provides cell culture production and research services to pharmaceutical and biotechnology companies as well as academic institutions.

Founded in 1990, Paragon is a preclinical contract research organization located at The Johns Hopkins Bayview Research Campus in Baltimore, MD.
Our mission is to partner with Pharmaceutical and Biotechnology companies as well as Academic labs in accelerating genomics and proteomics based drug discovery. We have anticipated the outsourcing needs?of these sectors and have worked diligently in structuring an integrated series of services in response to these needs.

The hallmark of our success is our ability to function as an extension of our clients own laboratories, where the clients are in control of their projects and all work is performed under strict confidentiality.
Cell Culture & Fermentation Services
Paragon maintains a cell bank of mammalian and insect cells as well as bacterial strains which are utilized in research projects, for functional assays and assay development, for recombinant protein expression, for production of monoclonal antibodies, or as a source for sub-cellular fractions - purification of organelles, Hela nuclear extracts, and membrane preps.
  

Company News

Paragon Bioservices initiates expansion plans and begins construction of new facilities

Paragon Bioservices to Attend the Following Conferences:

Click Here to Request a Meeting during the Event
 
August 5th & 6th -
IBC's Drug Discovery & Development of Innovative Therapeutics (DDT) Conference
 

October 22nd to 24th -
2008 Mid-Atlantic Bio Conference
 

Recombinant Protein Expression
Using multiple expression systems, Paragon has the capacity to produce up to gram quantities of recombinant proteins, including bacteria/yeast, baculovirus, and mammalian expression systems. Whether you're focused on lead discovery, production of identified targets for high throughput screening, or characterization of interesting gene products, we can help.
 
Protein Purification
A critical aspect in biopharmaceutical development is that expected functional activity must be associated with a single protein and that a formulation must be devoid of any contaminants including LPS, host cell DNA, viruses, etc. It is imperative, therefore, that therapeutic proteins, recombinant vaccines and diagnostic protein reagents be produced while achieving the highest level of purity possible.
Combining its skills developed over the last 12 years in protein biochemistry, analytical chemistry, and funct?onal assays, Paragon delivers efficient and cost effective solutions in protein purification and process development under Good Laboratory Practices in anticipation of future GMP manufacturing needs.
 
Proteomics Services - Protein Characterization
Paragon is meeting the "proteomics" challenge - a new paradigm in pharmaceutical development involving the systematic study of the protein complement - the proteome, by providing our clients with such research services as purification of organelles and 2-D gel electrophoresis.
 
Virus Production & Purification
Paragon's capabilities in virus production and purification attempts to address critical national public health needs, including gene therapy (adenovirus and adeno-associated viruses - AAV's), recombinant vaccines (virus-like particles - VLP's), infectious diseases (bacteriophages). We further seek to serve our national security imperative of bioterrorism control via the production of simulant organisms.
 
Process Development
Technological advances in genomics, proteomics, target validation, and lead compound identification have created a substantial need for contract services along the entire length of the development pipeline. Paragon is a GLP-compliant, cost-effective, and expedient outsourcing partner to assist you through drug discovery and preclinical development.
 
Functional Assays & Assay Development
Outsourcing your in vitro, ex vivo, and in vivo biological assay needs to Paragon Bioservices frees up your capacity to allow you to pursue additional leads for drug development.
 
Histology & Immunohistochemistry
With average turnaround of five to seven days, Paragon offers histology services and a variety of special stains - plus on-site electron microscopy services.
 
 

Cell Culture & Fermentation Services
Recombinant Protein Expression | Protein Purification
Proteomics Services - Protein Characterization
Virus Production & Purification | Process Development
Functional Assays & Assay Development | Histology & Immunohistochemistry

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Home Page - Paragon Bioservices  Paragon Bioservices, Inc - Johns Hopkins Bayview Research Campus
Alpha Center - 5210 Eastern Avenue - Baltimore, Maryland 21224
800.545.6569 - 410.550.2919 - 410.550.2924 (fax)
NIH BPA#: 263-00054123 - www.paragonbioservices.com - pbi@paragonbioservices.com

© 2003 Paragon Bioservices, Inc.